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Article

Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia.

Gastroenterology - 1 Apr 2009

Nam Ki Taek, Lee Hyuk-Joon, Mok Hoyin, Romero-Gallo Judith, Crowe James E, Peek Richard M, Goldenring James R

Abstract excerpt

BACKGROUND & AIMS: The loss of parietal cells from the fundic mucosa leads to the emergence of metaplastic lineages associated with an increased susceptibility to neoplastic transformation. Both intestinal metaplasia (IM) and spasmolytic polypeptide (TFF2/SP) expressing metaplasia (SPEM) have bee...

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Source

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Identifiers

PMID: 19230855
DOI: 10.1053/j.gastro.2008.12.037
PMCID: PMC2844775

Genes

TFF2
TFF3
MUC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19230855-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia.PMID 19230855Read ↗

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