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Article

Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia.

The Journal of clinical investigation - 1 Aug 2016

Ding Lin, Hayes Michael M, Photenhauer Amanda, Eaton Kathryn A, Li Qian, Ocadiz-Ruiz Ramon, Merchant Juanita L

Abstract excerpt

Chronic Helicobacter pylori infection triggers neoplastic transformation of the gastric mucosa in a small subset of patients, but the risk factors that induce progression to gastric metaplasia have not been identified. Prior to cancer development, the oxyntic gastric glands atrophy and are replaced by metaplastic cells in response to chronic gastritis. Previously, we identified schlafen 4 (Slfn4) as a GLI1 target...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27427984
DOI: 10.1172/JCI82529
PMCID: PMC4966326

Genes

GLI1
SHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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