Article
Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry.
BMC medical genetics - 19 Feb 2009
Vogel Carla I G, Greene Brandon, Scherag André, Müller Timo D, Friedel Susann, Grallert Harald, Heid Iris M, Illig Thomas, Wichmann H-Erich, Schäfer Helmut, Hebebrand Johannes, Hinney Anke
Abstract excerpt
BACKGROUND: A recent genome-wide association (GWA) study of U.S. Caucasians suggested that eight single nucleotide polymorphisms (SNPs) in CTNNBL1 are associated with obesity and increased fat mass. We analysed the respective SNPs in data from our previously published GWA for early onset obesity (case-control design), in GWA data from a population-based cohort of adults, and in an independent family-based obesity...
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