Article
Genetics of non-syndromic childhood obesity and the use of high-throughput DNA sequencing technologies.
Journal of diabetes and its complications - 1 Oct 2017
da Fonseca Ana Carolina Proença, Mastronardi Claudio, Johar Angad, Arcos-Burgos Mauricio, Paz-Filho Gilberto
Abstract excerpt
BACKGROUND: Childhood obesity is a serious public health problem associated with the development of several chronic diseases, such as type 2 diabetes mellitus, dyslipidemia, and hypertension. The elevated prevalence of obesity is mostly due to inadequate diet and lifestyle, but it is also influenced by genetic factors. OBJECTIVES: To review recent advances in the field of the genetics of obesity. We summarize the...
Topics
- Child
- DNA
- Genetic Association Studies
- Genetic Linkage
- Genetic Predisposition to Disease
- Genetic Testing
- Genome-Wide Association Study
- High-Throughput Nucleotide Sequencing
- Humans
- Models, Genetic