Article
Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes.
BMC medical genetics - 26 Feb 2009
Andreasen Camilla Helene, Mogensen Mette Sloth, Borch-Johnsen Knut, Sandbaek Annelli, Lauritzen Torsten, Almind Katrine, Hansen Lars, Jørgensen Torben, Pedersen Oluf, Hansen Torben
Abstract excerpt
BACKGROUND: A genome-wide scan in unrelated US Caucasians identified rs7001819 upstream of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) and multiple variants within catenin (cadherin-associated protein), beta-like 1 (CTNNBL1) to associate strongly with body mass index (BMI). The most significantly associating variants within CTNNBL1 including rs6013029 and rs6020846 were additionally confirmed to associate...
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