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Article

Trifluoroethanol reveals helical propensity at analogous positions in cytoplasmic domains of three connexins.

Biopolymers - 1 Jan 2009

Fort Alfredo G, Spray David C

Abstract excerpt

Cytoplasmic domains of gap junction proteins (connexins) are involved in channel gating, voltage and pH sensitivity, and contain binding sites for partner proteins. However, their secondary structure is incompletely characterized and comparisons among the connexins is totally lacking. Circular dichroism (CD) was used to study the conformational properties of synthetic peptides corresponding to the highly...

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PMID: 19226516
DOI: 10.1002/bip.21166
PMCID: PMC3645883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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