Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oligomerization of a peptide derived from the transmembrane region of the sodium pump gamma subunit: effect of the pathological mutation G41R.

Journal of molecular biology - 20 Sept 2002

Therien Alex G, Deber Charles M

Abstract excerpt

The Na,K-ATPase, or sodium pump, is a ubiquitously expressed membrane-bound enzyme that controls the transmembrane (TM) gradients of sodium and potassium ions in animal cells. The enzyme comprises two subunits, alpha and beta, and in the kidney, is also associated with a small single-spanning membrane protein, the gamma subunit. This 65 amino acid residues protein has been linked to a form of dominant renal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Circular Dichroism
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glycine

Share to Kidney Diseases

Share to Peptide Fragments

Share to Protein Conformation

Share to Sodium-Potassium-Exchanging ATPase

Source

Identifiers

PMID: 12225751
DOI: 10.1016/s0022-2836(02)00781-7

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oligomerization of a peptide derived from the transmembrane region of the sodium pump gamma subunit: effect of the pathological mutation G41R.PMID 12225751Read ↗

Modulation of Na,K-ATPase by the gamma subunit: studies with transfected cells and transmembrane mimetic peptides.Semantic proximity Read ↗

Visualizing the impact of disease-associated mutations on G protein–nucleotide interactionsSemantic proximity Read ↗

Effects of a polar amino acid substitution on helix formation and aggregate size along the detergent-induced peptide folding pathway.Semantic proximity Read ↗

Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II.Semantic proximity Read ↗

Differential regulation of renal Na,K-ATPase by splice variants of the gamma subunit.Semantic proximity Read ↗

Mutation of a conserved proline residue in the beta-subunit ectodomain prevents Na(+)-K(+)-ATPase oligomerization.Semantic proximity Read ↗

Characterization of Salt-Induced Oligomerization of Human β2-Microglobulin at Low pH.Semantic proximity Read ↗

Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I.Semantic proximity Read ↗

Na,K-ATPase from mice lacking the gamma subunit (FXYD2) exhibits altered Na+ affinity and decreased thermal stability.Semantic proximity Read ↗

Modulation of the oligomerization of myelin proteolipid protein by transmembrane helix interaction motifs.Semantic proximity Read ↗

Expression, purification, and structural analysis of the full-length human integral membrane protein γ-sarcoglycan.Semantic proximity Read ↗

The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.