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How Can Genetic Studies Help Us to Understand Links Between Birth Weight and Type 2 Diabetes?

Current diabetes reports - 1 Apr 2017

Beaumont Robin N, Horikoshi Momoko, McCarthy Mark I, Freathy Rachel M

Abstract excerpt

PURPOSE OF REVIEW: In observational epidemiology, both low and high birth weights are associated with later type 2 diabetes. The mechanisms underlying the associations are poorly understood. We review evidence for the roles of genetic and non-genetic factors linking both sides of the birth weight distribution to risk of type 2 diabetes, focusing on contributions made by the most recent genome-wide association...

Topics

Birth Weight
Diabetes Mellitus, Type 2
Fetal Development
Genetic Loci
Genome-Wide Association Study
Genotype
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28293907
DOI: 10.1007/s11892-017-0852-9
PMCID: PMC5350261

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