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Article

Essential role of nuclear localization for yeast Ulp2 SUMO protease function.

Molecular biology of the cell - 1 Apr 2009

Kroetz Mary B, Su Dan, Hochstrasser Mark

Abstract excerpt

The SUMO protein is covalently attached to many different substrates throughout the cell. This modification is rapidly reversed by SUMO proteases. The Saccharomyces cerevisiae SUMO protease Ulp2 is a nuclear protein required for chromosome stability and cell cycle restart after checkpoint arrest. Ulp2 is related to the human SENP6 protease, also a nuclear protein. All members of the Ulp2/SENP6 family of SUMO...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19225149
DOI: 10.1091/mbc.e08-10-1090
PMCID: PMC2669027

Genes

SENP6

Provenance

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Essential role of nuclear localization for yeast Ulp2 SUMO protease function.PMID 19225149Read ↗

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