Article
SUMO conjugation and deconjugation.
Molecular & general genetics : MGG - 1 Jun 2000
Schwienhorst I, Johnson E S, Dohmen R J
Abstract excerpt
Ligation of the ubiquitin-like protein SUMO (Smt3p) to other proteins is essential for viability of the yeast Saccharomyces cerevisiae. Like ubiquitin (Ub), SUMO undergoes ATP-dependent activation by a specific activating enzyme. SUMO-activating enzyme is a heterodimer composed of Uba2p and Aos1p, polypeptides with sequence similarities, respectively, to the C- and N-terminal parts of Ub-activating enzyme. To...
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