Article
NUCLEAR PORE ANCHOR, the Arabidopsis homolog of Tpr/Mlp1/Mlp2/megator, is involved in mRNA export and SUMO homeostasis and affects diverse aspects of plant development.
The Plant cell - 1 May 2007
Xu Xianfeng Morgan, Rose Annkatrin, Muthuswamy Sivaramakrishnan, Jeong Sun Yong, Venkatakrishnan Sowmya, Zhao Qiao, Meier Iris
Abstract excerpt
Vertebrate Tpr and its yeast homologs Mlp1/Mlp2, long coiled-coil proteins of nuclear pore inner basket filaments, are involved in mRNA export, telomere organization, spindle pole assembly, and unspliced RNA retention. We identified Arabidopsis thaliana NUCLEAR PORE ANCHOR (NUA) encoding a 237-kD protein with similarity to Tpr. NUA is located at the inner surface of the nuclear envelope in interphase and in the...
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