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Article

Hepatitis B virus mutations potentially conferring adefovir/tenofovir resistance in treatment-naive patients.

World journal of gastroenterology - 14 Feb 2009

Pastor Rebecca, Habersetzer Francois, Fafi-Kremer Samira, Doffoel Michel, Baumert Thomas-F, Gut Jean-Pierre, Stoll-Keller Francoise, Schvoerer Evelyne

Abstract excerpt

Anti-hepatitis B virus (HBV) therapy leads to the emergence of mutant viral strains during the treatment of chronic hepatitis B with nucleos(t)ides analogues. The existence of HBV variants with primary antiviral resistance may be important for treatment choice. We studied two patients with chronic HBV infection by sequencing the HBV polymerase gene. They had adefovir- and tenofovir-related mutations in the viral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19222103
DOI: 10.3748/wjg.15.753
PMCID: PMC2653447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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