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Article

Characterization of the tenofovir resistance-associated mutations in the hepatitis B virus isolates across genotypes A to D.

Antiviral research - 1 Jul 2022

Liu Tingting, Sun Qingsong, Gu Jiaqi, Cen Shan, Zhang Quan

Abstract excerpt

Tenofovir is wildly used to treat chronic hepatitis B (CHB) infection due to good potency and high genetic barrier to drug resistance. To date, it remains controversial whether hepatitis B virus (HBV) could be resistant to tenofovir. This study used multiple HBV isolates across genotypes A to D to characterize the reported tenofovir resistance-associated mutations identified from a few clinical case reports. Our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35644506
DOI: 10.1016/j.antiviral.2022.105348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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