Article

Drug Resistance Mutations in the Polymerase Gene of Hepatitis B Virus in Three Generations of Patients with Chronic Hepatitis B

2023-12-05

Abstract excerpt

<title>Abstract</title> <p>Hepatitis B virus polymerase proofreading defects lead to frequent DNA mutations in the hepatitis B virus genome and treatment resistance. This research aimed to investigate drug-resistant mutations in three generations of chronic hepatitis B patients. Based on the inclusion criteria, 90 HBV patients in northeastern Iran were divided into three groups. HBV DNA, liver function tests, ser...

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Literature Corpus work: 7cf8b4e2-97bf-5e9c-b549-cffd14933695
DOI: 10.21203/rs.3.rs-3676026/v1

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