Article
Hepatitis B virus reverse transcriptase mutations in treatment Naïve chronic hepatitis B patients.
Journal of medical virology - 1 Jul 2013
Singla Bhupesh, Chakraborti Anuradha, Sharma Bal Krishan, Kapil Shweta, Chawla Yogesh K, Arora Sunil K, Das Ashim, Dhiman Radha K, Duseja Ajay
Abstract excerpt
Mutations in the reverse transcriptase (RT) region of the hepatitis B virus (HBV) genome lead to decreased susceptibility to nucleos(t)ide analogs approved for treatment of HBV infection. The aim of this study was to detect and analyze pre-existing HBV RT mutations in treatment naïve patients wit...
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