Article
Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.
Arthritis and rheumatism - 1 Jun 1998
Glant T T, Cs-Szabó G, Nagase H, Jacobs J J, Mikecz K
Abstract excerpt
OBJECTIVE: To find an "unlimited" source of antigenic material (aggrecan) for arthritis induction in BALB/c mice; to analyze the specificities of immune reactions to aggrecan and type II collagen in 2 arthritis-susceptible murine strains, BALB/c mice for proteoglycan (aggrecan)-induced arthritis...
Topics
- Adult
- Aged
- Aged, 80 and over
- Aggrecans
- Animals
- Arthritis
- Arthritis, Rheumatoid
- Cartilage, Articular
- Disease Progression
- Extracellular Matrix Proteins
- Female
- Fetus
