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Article

Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.

Arthritis and rheumatism - 1 Jun 1998

Glant T T, Cs-Szabó G, Nagase H, Jacobs J J, Mikecz K

Abstract excerpt

OBJECTIVE: To find an "unlimited" source of antigenic material (aggrecan) for arthritis induction in BALB/c mice; to analyze the specificities of immune reactions to aggrecan and type II collagen in 2 arthritis-susceptible murine strains, BALB/c mice for proteoglycan (aggrecan)-induced arthritis and DBA/1j mice for collagen-induced arthritis; to compare the histopathologic features of arthritis induced by...

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Source

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PMID: 9627010
DOI: 10.1002/1529-0131(199806)41:6<1007::AID-ART7>3.0.CO;2-6

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