Article
Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease.
Arthritis and rheumatism - 1 Mar 2001
Glant T T, Bárdos T, Vermes C, Chandrasekaran R, Valdéz J C, Otto J M, Gerard D, Velins S, Lovász G, Zhang J, Mikecz K, Finnegan A
Abstract excerpt
OBJECTIVE: To identify and screen the level of arthritis susceptibility in C3H murine strains known to be resistant to proteoglycan (aggrecan)-induced arthritis, and to measure and correlate various immunologic and inflammatory parameters with susceptibility to either arthritis or spondylitis in various C3H substrains. METHODS: Mice of 10 C3H substrains (subcolonies) were immunized with cartilage proteoglycan...
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