Article
A bHLH code for cardiac morphogenesis.
Pediatric cardiology - 1 Apr 2010
Conway Simon J, Firulli Beth, Firulli Anthony B
Abstract excerpt
Cell specification and differentiation of cardiomyocytes from mesodermal precursors is orchestrated by epigenetic and transcriptional inputs throughout heart formation. Of the many transcription factor super families that play a role in this process, the basic Helix-loop Helix (bHLH) family of proteins is well represented. The bHLH protein by design allows for dimerization-both as homodimers and heterodimers with...
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