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Article

The vHNF1 homeodomain protein establishes early rhombomere identity by direct regulation of Kreisler expression.

Mechanisms of development - 1 Dec 2005

Kim Florence A, Sing l Angela, Kaneko Tomomi, Bieman Melissa, Stallwood Nicole, Sadl Virginia S, Cordes Sabine P

Abstract excerpt

The early transcriptional hierarchy that subdivides the vertebrate hindbrain into seven to eight segments, the rhombomeres (r1-r8), is largely unknown. The Kreisler (MafB, Krml1, Val) gene is earliest gene expressed in an r5/r6-restricted manner and is essential for r5 and r6 development. We have identified the S5 regulatory element that directs early Kreisler expression in the future r5/r6 domain in 0-10 somite...

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Share to Conserved Sequence
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Hepatocyte Nuclear Factor 1

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Share to MafB Transcription Factor

Share to Mice, Transgenic

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Identifiers

PMID: 16274963
DOI: 10.1016/j.mod.2005.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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