Article
Plasma membrane calcium ATPase required for semicircular canal formation and otolith growth in the zebrafish inner ear.
The Journal of experimental biology - 1 Mar 2009
Cruz Shelly, Shiao Jen-Chieh, Liao Bo-Kai, Huang Chang-Jen, Hwang Pung-Pung
Abstract excerpt
Fish otoliths consist of >90% calcium carbonate, the accretion of which depends on acellular endolymph. This study confirms the presence of plasma membrane calcium ATPase 1a isoform (Atp2b1a) in the auditory and vestibular system of a teleost fish. As shown by in situ hybridization, zebrafish atp2b1a is expressed mainly in larval otic placode and lateral-line neuromast as well as in the hair cells within the...
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