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Article

Synthesis and SAR of piperazinyl-N-phenylbenzamides as inhibitors of hepatitis C virus RNA replication in cell culture.

Bioorganic & medicinal chemistry letters - 15 Mar 2009

Conte Immacolata, Giuliano Claudio, Ercolani Caterina, Narjes Frank, Koch Uwe, Rowley Michael, Altamura Sergio, De Francesco Raffaele, Neddermann Petra, Migliaccio Giovanni, Stansfield Ian

Abstract excerpt

The RNA replication machinery of HCV is a multi-subunit membrane-associated complex. NS5A has emerged as an active component of HCV replicase, possibly involved in regulation of viral replication and resistance to the antiviral effect of interferon. We report here substituted piperazinyl-N-(aryl)...

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Identifiers

PMID: 19216075
DOI: 10.1016/j.bmcl.2009.01.066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19216075-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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