Chapter 12. Analysis of nonfunctional ribosomal RNA decay in Saccharomyces cerevisiae.

doi:10.1016/S0076-6879(08)02412-9

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Article

Chapter 12. Analysis of nonfunctional ribosomal RNA decay in Saccharomyces cerevisiae.

Methods in enzymology - 1 Jan 2008

Cole Sarah E, LaRiviere Frederick J

Abstract excerpt

Mature rRNA are normally extremely stable in rapidly growing cells. However, studies show that some mature rRNA in Saccharomyces cerevisiae are, in fact, turned over quite rapidly by the nonfunctional rRNA decay (NRD) pathway. NRD eliminates the RNA component of mature but defective ribosomal subunits and ribosomes. NRD was discovered using rDNA reporter plasmids to express and track the fate of rRNA containing...

Topics

Kinetics
Mutation
Plasmids
RNA Stability
RNA, Ribosomal
Saccharomyces cerevisiae

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Open in PubMed

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PMID: 19215762
DOI: 10.1016/S0076-6879(08)02412-9

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