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Article

rRNA maturation in yeast cells depleted of large ribosomal subunit proteins.

PloS one - 11 Dec 2009

Pöll Gisela, Braun Tobias, Jakovljevic Jelena, Neueder Andreas, Jakob Steffen, Woolford John L, Tschochner Herbert, Milkereit Philipp

Abstract excerpt

The structural constituents of the large eukaryotic ribosomal subunit are 3 ribosomal RNAs, namely the 25S, 5.8S and 5S rRNA and about 46 ribosomal proteins (r-proteins). They assemble and mature in a highly dynamic process that involves more than 150 proteins and 70 small RNAs. Ribosome biogenesis starts in the nucleolus, continues in the nucleoplasm and is completed after nucleo-cytoplasmic translocation of the...

Topics

Blotting, Northern
Cytoplasm
Endonucleases
Models, Molecular
Mutation
RNA 3' End Processing
RNA Precursors
RNA Transport
RNA, Ribosomal
RNA, Ribosomal, 5.8S
Ribosome Subunits, Large

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 20011513
DOI: 10.1371/journal.pone.0008249
PMCID: PMC2788216

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