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Article

Stability of two beta-tropomyosin isoforms: effects of mutation Arg91Gly.

Journal of muscle research and cell motility - 1 Jan 2008

Nevzorov Ilya, Redwood Charles, Levitsky Dmitrii

Abstract excerpt

In order to comprehend the domain structure of two beta-tropomyosin (beta-Tm) isoforms (skeletal muscle and smooth muscle beta-Tm) and the influence of the disease-causing mutation Arg91Gly on it, we studied the thermal unfolding of these tropomyosin species by means of differential scanning calorimetry (DSC). Our results show that the studied point mutation dramatically decreases thermal stability of a...

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Identifiers

PMID: 19214762
DOI: 10.1007/s10974-009-9171-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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