Article
Genetic variations in apoptosis pathway and the risk of ovarian cancer.
Oncotarget - 30 Aug 2016
Xie Hui, Tao Wade, Wu Xifeng, Gu Jian
Abstract excerpt
BACKGROUND: Apoptosis is a highly conserved form of cell death and aberrant regulation of apoptotic cell death mechanisms leads to variety of major human diseases, especially tumor formation. Genetic variations in apoptosis genes may increase susceptibility to ovarian cancer. RESULTS: In individual SNP analysis, 12 SNPs in 5 apoptosis pathway genes were significantly associated with ovarian cancer risk after...
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