Article
beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium.
American journal of respiratory cell and molecular biology - 1 Nov 2009
Zemke Anna C, Teisanu Roxana M, Giangreco Adam, Drake Jeff A, Brockway Brian L, Reynolds Susan D, Stripp Barry R
Abstract excerpt
Signaling by Wnt/beta-catenin regulates self-renewal of tissue stem cells in the gut and, when activated in the embryonic bronchiolar epithelium, leads to stem cell expansion. We have used transgenic and cell type-specific knockout strategies to determine roles for beta-catenin-regulated gene exp...
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