Article
Tracheal Basal cells: a facultative progenitor cell pool.
The American journal of pathology - 1 Jul 2010
Cole Brook B, Smith Russell W, Jenkins Kimberly M, Graham Brian B, Reynolds Paul R, Reynolds Susan D
Abstract excerpt
Analysis of lineage relationships in the naphthalene-injured tracheal epithelium demonstrated that two multipotential keratin 14-expressing cells (K14ECs) function as progenitors for Clara and ciliated cells. These K14EC were distinguished by their self-renewal capacity and were hypothesized to reside at the stem and transit amplifying tiers of a tissue-specific stem cell hierarchy. In this study, we used gene...
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