Article
Context-dependent differentiation of multipotential keratin 14-expressing tracheal basal cells.
American journal of respiratory cell and molecular biology - 1 Aug 2011
Ghosh Moumita, Brechbuhl Heather M, Smith Russell W, Li Bilan, Hicks Douglas A, Titchner Timothy, Runkle Christine M, Reynolds Susan D
Abstract excerpt
Multipotential (MP) differentiation is one characteristic of a tissue-specific stem cell (TSC). Lineage tracing of tracheobronchial basal cells after naphthalene (NA) injury or in the postnatal period demonstrated that basal cells were MP progenitors for Clara-like and ciliated cells. These studies, as well as reports of spatially restricted, label-retaining basal cells, and MP differentiation by human bronchial...
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