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Article

Ciliated epithelial cell lifespan in the mouse trachea and lung

17 May 2008

Abstract excerpt

The steady-state turnover of epithelial cells in the lung and trachea is highly relevant to investigators who are studying endogenous stem cells, manipulating gene expression in vivo, or using viral vectors for gene therapy. However, the average lifetime of different airway epithelial cell types has not previously been assessed using currently available genetic techniques. Here, we use Cre/loxP genetic technology...

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Identifiers

PMID: 18487354
DOI: 10.1152/ajplung.90209.2008

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