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Article

Conditional stabilization of beta-catenin expands the pool of lung stem cells.

Stem cells (Dayton, Ohio) - 1 May 2008

Reynolds Susan D, Zemke Anna C, Giangreco Adam, Brockway Brian L, Teisanu Roxana M, Drake Jeffrey A, Mariani Thomas, Di Peter Y P, Taketo Mark M, Stripp Barry R

Abstract excerpt

Maintenance of classic stem cell hierarchies is dependent upon stem cell self-renewal mediated in part by Wnt/beta-catenin regulation of the cell cycle. This function is critical in rapidly renewing tissues due to the obligate role played by the tissue stem cell. However, the stem cell hierarchy...

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Identifiers

PMID: 18356571
DOI: 10.1634/stemcells.2008-0053
PMCID: PMC2773682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18356571-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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