Article
A proneural gene controls C. elegans neuroblast asymmetric division and migration.
FEBS letters - 2 Apr 2014
Zhu Zhiwen, Liu Jianhong, Yi Peishan, Tian Dong, Chai Yongping, Li Wei, Ou Guangshuo
Abstract excerpt
Proneural genes control the generation of neuroblasts from the neuroepithelium, but their functions in neuroblast asymmetric division and migration remain elusive. Here, we identified Caenorhabditiselegans mutants of a proneural transcription factor (TF) lin-32, in which Q neuroblasts are produced. We showed that LIN-32 functions in parallel with a storkhead TF, HAM-1, to regulate Q neuroblast asymmetric...
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