Article
Detection of drug-resistant HIV-1 strains.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Kiessling Ann A, Eyre S J, Desmarais B D
Abstract excerpt
Human immunodeficiency virus (HIV-1) encodes proteins essential to its replication cycle. Reverse transcriptase, protease, and viral envelope gp120 are three proteins that have been targeted for antiviral drug development. Eleven inhibitors of reverse transcriptase, seven inhibitors of protease, and one inhibitor of viral envelope binding have been approved for use. Antiretroviral therapy has reversed the...
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