Article
Growth hormone dose in growth hormone-deficient adults is not associated with IGF-1 gene polymorphisms.
Pharmacogenomics - 1 Feb 2009
Meyer Silke, Schaefer Stephan, Ivan Diana, Stolk Lisette, Arp Pascal, Uitterlinden André G, Nawroth Peter P, Plöckinger Ursula, Stalla Günter K, Tuschy Ulrich, Weber Matthias M, Weise Alexander, Pfützner Andreas, Kann Peter H
Abstract excerpt
AIMS: Several SNPs and a microsatellite cytosine-adenine repeat promoter polymorphism of the IGF-1 gene have been reported to be associated with circulating IGF-1 serum concentrations. Variance in IGF-1 concentrations due to genetic variations may affect different response to growth hormone (GH)...
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