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Article

Association of COLIA1 Sp1 polymorphism with the effect of subcutaneously injected recombinant hGH in GH-deficient adults.

Pharmacogenomics - 1 Aug 2008

Meyer Silke, Haist Marlitt, Schaefer Stephan, Ivan Diana, Ittner Jochen R, Nawroth Peter P, Plöckinger Ursula, Stalla Günter K, Tuschy Ulrich, Weber Matthias M, Weise Alexander, Pfützner Andreas, Habbe Nils, Kann Peter H

Abstract excerpt

OBJECTIVE: Collagen type I is a common structural protein in bone and skin. Similar to its association with the mechanical properties of the skeleton and, thus, bone-fracture risk, the collagen type I alpha (COLIA)-1 specific protein (Sp)-1 polymorphism may be related to variations in the collagen type I-containing subcutaneous tissue and its biological properties. In this study, we analyzed a possible influence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18681778
DOI: 10.2217/14622416.9.8.1017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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