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Article

Counterselection of GATC sequences in enterobacteriophages by the components of the methyl-directed mismatch repair system.

Journal of molecular evolution - 1 Aug 1991

Deschavanne P, Radman M

Abstract excerpt

Weak to severe deficit of GATC sequences in the DNA of enterobacteriophages appears to be correlated with their undermethylation during growth in dam+ (GATC ade-methylase) bacteria. This observation is corroborated by the sequence analysis showing no evidence for site-specific mutagenicity of 6meAde. The MutH protein of the methyl-directed mismatch repair system recognizes and cleaves the undermethylated GATC...

Topics

Base Sequence
Coliphages
DNA Repair
DNA, Viral
Escherichia coli
Methylation
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1920448
DOI: 10.1007/BF02193626

Genes

GATC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1920448-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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