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Article

GATC flanking sequences regulate Dam activity: evidence for how Dam specificity may influence pap expression.

Journal of molecular biology - 20 Jan 2006

Peterson Stacey N, Reich Norbert O

Abstract excerpt

Escherichia coli DNA adenine methyltransferase (Dam) plays essential roles in DNA replication, mismatch repair and gene regulation. The differential methylation by Dam of the two GATC sequences in the pap promoter regulates the expression of pili genes necessary for uropathogenic E.coli cellular adhesion. Dam processively methylates GATC sites in various DNA substrates, yet the two pap GATC sites are not...

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Source

Identifiers

PMID: 16321401
DOI: 10.1016/j.jmb.2005.11.003

Genes

GATC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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