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Article

Refined atomic structures of N9 subtype influenza virus neuraminidase and escape mutants.

Journal of molecular biology - 20 Sept 1991

Tulip W R, Varghese J N, Baker A T, van Donkelaar A, Laver W G, Webster R G, Colman P M

Abstract excerpt

The crystal structure of the N9 subtype neuraminidase of influenza virus was refined by simulated annealing and conventional techniques to an R-factor of 0.172 for data in the resolution range 6.0 to 2.2 A. The r.m.s. deviation from ideal values of bond lengths is 0.014 A. The structure is similar to that of N2 subtype neuraminidase both in secondary structure elements and in their connections. The...

Topics

Antigens, Bacterial
Influenza A virus
Models, Molecular
Mutation
N-Acetylneuraminic Acid
Neuraminidase
Protein Binding
Protein Conformation
Sialic Acids
Surface Properties
Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

X-Ray Diffraction

Source

Identifiers

PMID: 1920429
DOI: 10.1016/0022-2836(91)80069-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1920429-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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