Crystallization and preliminary X-ray diffraction studies of a monoclonal antibody Fab fragment specific for an influenza virus haemagglutinin and of an escape mutant of that haemagglutinin.

doi:10.1016/0022-2836(90)90378-Y

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Article

Crystallization and preliminary X-ray diffraction studies of a monoclonal antibody Fab fragment specific for an influenza virus haemagglutinin and of an escape mutant of that haemagglutinin.

Journal of molecular biology - 5 Dec 1990

Bizebard T, Mauguen Y, Petek F, Rigolet P, Skehel J J, Knossow M

Abstract excerpt

Preliminary crystallographic data are given for two molecules involved in the interaction between the humoral immune response and the influenza virus. These molecules are the Fab fragment of an antibody specific for the haemagglutinin of influenza virus strain X31 (Hong Kong 1/68 (H3N2)) and a mu...

Topics

Animals
Antibodies, Monoclonal
Antigenic Variation
Crystallization
Hemagglutinin Glycoproteins, Influenza Virus
Hemagglutinins, Viral
Immunoglobulin Fab Fragments
Mice
Mutation
X-Ray Diffraction

Source

Open in PubMed

Identifiers

PMID: 2258927
DOI: 10.1016/0022-2836(90)90378-Y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2258927-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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