Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis.

The Journal of biological chemistry - 3 Apr 2009

Park Ann Y J, Shen Tang-Long, Chien Shu, Guan Jun-Lin

Abstract excerpt

Focal adhesion kinase (FAK) is the major cytoplasmic tyrosine kinase in focal adhesions and a critical mediator of integrin signaling in a variety of cells, including endothelial cells (ECs). Here we describe a new function for FAK in the regulation of centrosome functions in a Ser-732 phosphoryl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrosome
Share to Cytoplasm
Share to Dyneins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Focal Adhesion Protein-Tyrosine Kinases

Share to Mitosis

Share to Neovascularization, Pathologic

Share to Phosphoserine

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 19201755
DOI: 10.1074/jbc.M809040200
PMCID: PMC2666594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19201755-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis.PMID 19201755Read ↗

Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration.Semantic proximity Read ↗

New Insights on the Nuclear Functions and Targeting of FAK in CancerSemantic proximity Read ↗

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration.Semantic proximity Read ↗

Cortactin as a target for FAK in the regulation of focal adhesion dynamics.Semantic proximity Read ↗

FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation.Semantic proximity Read ↗

Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development.Semantic proximity Read ↗

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development and TherapySemantic proximity Read ↗

Focal adhesion kinase and cancer.Semantic proximity Read ↗

Understanding the Roles of FAK in CancerSemantic proximity Read ↗

Control of motile and invasive cell phenotypes by focal adhesion kinase.Semantic proximity Read ↗

Abundant Focal Adhesion Kinase Causes Aberrant Neuronal Migration Via Its Phosphorylation at Tyr925.Semantic proximity Read ↗

Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.