Article
Deletion at Dickkopf (dkk)-3 locus (11p15.2) is related with lower lymph node metastasis and better prognosis in head and neck squamous cell carcinomas.
Oncology research - 1 Jan 2008
Katase Naoki, Gunduz Mehmet, Beder Levent, Gunduz Esra, Lefeuvre Mathieu, Hatipoglu Omer Faruk, Borkosky Silvia Susana, Tamamura Ryo, Tominaga Susumu, Yamanaka Noboru, Shimizu Kenji, Nagai Noriyuki, Nagatsuka Hitoshi
Abstract excerpt
Head and neck squamous cell carcinoma (HNSCC) is a frequently occurring cancer, and despite improvement of its treatment methods, including chemotherapy, radiotherapy, and surgery, the improvement of survival remains poor. Recent advances in molecular biology of human cancer indicated various molecular abnormalities in HNSCC, including activation of oncogenes and inactivation of tumor suppressor genes (TSGs)....
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