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Article

DKK3 is a potential tumor suppressor gene in papillary thyroid carcinoma

23 May 2013

Abstract excerpt

The expression of the Dickkopf homolog 3 (DKK3) gene is downregulated in some human cancers, suggesting a possible tumor suppressor role of this gene. The role and regulation of DKK3 in thyroid cancer have not been examined. In this study, we explored the relationship of promoter methylation with the inactivation of DKK3 and tumor behaviors in papillary thyroid carcinoma (PTC). We used methylation-specific PCR...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Thyroid Cancer Diagnosis and Treatment

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Identifiers

PMID: 23702469
DOI: 10.1530/erc-13-0053

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