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Article

Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis.

Cancer biology & therapy - 1 Oct 2010

Lee Dong Jin, Schönleben Frank, Banuchi Victoria E, Qiu Wanglong, Close Lanny G, Assaad Adel M, Su Gloria H

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) remains a significant cause of morbidity and mortality. There has been a great interest in finding specific genomic changes which contribute to HNSCC tumorigenesis, especially within the chromosome 3p area, where high frequency of LOH (loss of heterozygosity) has been reported. However, tumor-suppressor genes that may account for the frequent LOH remain to be...

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Share to Adaptor Proteins, Signal Transducing
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 3

Share to Guanine Nucleotide Exchange Factors

Share to Head and Neck Neoplasms

Share to Loss of Heterozygosity

Share to Receptor Protein-Tyrosine Kinases

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20657180
DOI: 10.4161/cbt.10.7.12886
PMCID: PMC3093810

Genes

EPHA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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