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Article

A literature review on function and regulation mechanism of DKK4.

Journal of cellular and molecular medicine - 1 Mar 2021

Lou Xiaoli, Meng Yuchen, Hou Yanqiang

Abstract excerpt

Dickkopf-related protein 4 (DKK4) is a member of the dickkopf family and an inhibitor of the Wnt/β-catenin signalling pathway. This review surveyed the single nucleotide polymorphisms (SNPs), copy number variations (CNVs), hypermethylation, regulation mechanism, correlation with clinicopathological parameters and chemotherapeutic resistance of DKK4. The signal pathways involved in DKK4 mainly include...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33586359
DOI: 10.1111/jcmm.16372
PMCID: PMC7957263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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