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Article

Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex.

Neural development - 3 Feb 2009

Thomson Rachel E, Kind Peter C, Graham Nicholas A, Etherson Michelle L, Kennedy John, Fernandes Ana C, Marques Catia S, Hevner Robert F, Iwata Tomoko

Abstract excerpt

BACKGROUND: Fibroblast growth factors (Fgfs) are important regulators of cerebral cortex development. Fgf2, Fgf8 and Fgf17 promote growth and specification of rostromedial (frontoparietal) cortical areas. Recently, the function of Fgf15 in antagonizing Fgf8 in the rostral signaling center was also reported. However, regulation of caudal area formation by Fgf signaling remains unknown. RESULTS: In mutant mice with...

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Identifiers

PMID: 19192266
DOI: 10.1186/1749-8104-4-4
PMCID: PMC2661882

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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