Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patterning of frontal cortex subdivisions by Fgf17.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 2007

Cholfin Jeremy A, Rubenstein John L R

Abstract excerpt

The frontal cortex (FC) is the seat of higher cognition. The genetic mechanisms that control formation of the functionally distinct subdivisions of the FC are unknown. Using a set of gene expression markers that distinguish subdivisions of the newborn mouse FC, we show that loss of Fgf17 selectively reduces the size of the dorsal FC whereas ventral/orbital FC appears normal. These changes are complemented by a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice, Knockout
Share to Biomarkers
Share to Body Patterning

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 8

Share to Fibroblast Growth Factors

Share to Frontal Lobe

Share to Gene Expression Regulation, Developmental

Source

Open in PubMed Open full text

Identifiers

PMID: 17442747
DOI: 10.1073/pnas.0702225104
PMCID: PMC1863435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patterning of frontal cortex subdivisions by Fgf17.PMID 17442747Read ↗

Molecular mechanisms driving divergent development of the human frontal and visual cortex during prenatal developmentSemantic proximity Read ↗

Brain wiring and supragranular-enriched genes linked to protracted human frontal cortex developmentSemantic proximity Read ↗

FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis.Semantic proximity Read ↗

A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids.Semantic proximity Read ↗

Neuregulin signaling, cortical circuitry development and schizophreniaSemantic proximity Read ↗

Early developmental patterning sets the stage for brain evolution.Semantic proximity Read ↗

Morphological and functional midbrain phenotypes in Fibroblast Growth Factor 17 mutant mice detected by Mn-enhanced MRI.Semantic proximity Read ↗

Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathologySemantic proximity Read ↗

Molecular Specification of Claustro-Amygdalar and Paleocortical Neurons and ConnectivitySemantic proximity Read ↗

The cortical hem regulates the size and patterning of neocortex.Semantic proximity Read ↗

A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell typesSemantic proximity Read ↗

Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.