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A multifaceted interplay between virulence, drug resistance, and the phylogeographic landscape of Mycobacterium tuberculosis

28 Sept 2023

Abstract excerpt

ABSTRACT Latin-American Mediterranean (LAM) family is one of the most significant and global genotypes of Mycobacterium tuberculosis . Here, we used the murine model to study the virulence and lethality of the genetically and epidemiologically distinct LAM strains. The pathobiological characteristics of the four LAM strains (three drug resistant and one drug susceptible) and the susceptible reference strain H37Rv...

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PMID: 37768091
DOI: 10.1128/spectrum.01392-23

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