Article
Specific bacterial genotypes of Mycobacterium tuberculosis cause extensive dissemination and brain infection in an experimental model.
Tuberculosis (Edinburgh, Scotland) - 1 Jul 2010
Hernandez Pando Rogelio, Aguilar Diana, Cohen Ingrid, Guerrero Martha, Ribon Wellman, Acosta Patrícia, Orozco Hector, Marquina Brenda, Salinas Citlal, Rembao Daniel, Espitia Clara
Abstract excerpt
Meningeal tuberculosis is a severe type of extrapulmonary disease, which is thought to begin with respiratory infection, followed by hematogenous dissemination and brain infection. Host genetic susceptibility factors and specific mycobacterial substrains could be involved in its development. From an epidemiological study in Colombia, we selected three Mycobacterium tuberculosis clinical strains isolated from the...
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