Article
Evolution of the mouse H-2K region: a hot spot of mutation associated with genes transcribed in embryos and/or germ cells.
Genetics - 1 Mar 1992
Yeom Y I, Abe K, Artzt K
Abstract excerpt
Active gene transcription is known to promote genetic change in neighboring DNA. We reasoned that the change would be readily heritable if transcription was occurring in germ cells or early embryonic cells before the germ cells are set aside. The H-2K region of the major histocompatibility comple...
Topics
- Animals
- Biological Evolution
- Blotting, Southern
- Embryo, Mammalian
- Gene Expression
- Genetic Complementation Test
- Genetic Variation
- Germ Cells
- H-2 Antigens
- Haplotypes
- Intracellular Signaling Peptides and Proteins
- Kinetics