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Article

Polymorphic Variants 279R and 668Q Augment Activity of Matrix Metalloproteinase-9 in Breath Condensates of Children with Asthma.

Archivum immunologiae et therapiae experimentalis - 1 Apr 2017

Grzela Katarzyna, Zagórska Wioletta, Krejner Alicja, Litwiniuk Malgorzata, Zawadzka-Krajewska Anna, Kulus Marek, Grzela Tomasz

Abstract excerpt

Matrix metalloproteinase (MMP)-9 is involved in pathophysiology of asthma, mainly asthma-associated airway remodeling. Exhaled breath condensates (EBC) of asthmatics contain increased amounts of MMP-9 with activity higher, than in healthy controls. The increased activity of MMP-9 may originate from its excessive production and activation, but may also result from variations in MMP-9 structure, which are...

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PMID: 27395373
DOI: 10.1007/s00005-016-0412-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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