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Article

Analysis of MMP-2-735C/T (rs2285053) and MMP-9-1562C/T (rs3918242) Polymorphisms in the Risk Assessment of Developing Lung Cancer.

International journal of molecular sciences - 24 Jun 2023

Wadowska Katarzyna, Błasiak Piotr, Rzechonek Adam, Śliwińska-Mossoń Mariola

Abstract excerpt

Matrix metalloproteinase (MMP)-2 and -9 are gelatinases which are capable of degrading type IV collagen and have been linked to cancer invasion and metastatic development. MMP-2 and MMP-9 gene polymorphisms may affect their biological function, and thus their role in cancer development and progression. We analyzed the association of the polymorphism frequencies of MMP-2-735C/T and MMP-9-1562C/T with MMP-2 and...

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Case-Control Studies
Gene Frequency
Lung Neoplasms
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Polymorphism, Single Nucleotide

Risk Assessment

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Open in PubMed Open full text

Identifiers

PMID: 37445754
DOI: 10.3390/ijms241310576
PMCID: PMC10341518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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